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Seroquel is an antipsychotic medication used for treating conditions like schizophrenia. It does its job by restoring the balance between certain chemicals in the brain. This drug is taken through the mouth.

Overview and Uses

AstraZeneca introduced Seroquel in 2006 to be used for the treatment of schizophrenia. This first version of Seroquel was a sustained-release version. By 2007, the United States Food and Drug Administration (FDA) had approved this medication for the treatment of schizophrenia.

A year later, the FDA also approved Seroquel for the treatment of bipolar mania and bipolar depression. This was a historical moment, as this medication was the first FDA-approved, once-daily drug for acute bipolar, manic and depressive treatments.

Physicians use Seroquel to treat the following conditions:

  • Schizophrenia
  • Bipolar disorder
  • Depressive disorder
  • Mania

Action in the Body

Seroquel is part of a category of medications known as atypical antipsychotics. This medication controls mental conditions by altering the activity of certain substances in the brain. This way, the balance of certain brain chemicals is restored.

Consumption and Dosage

When taking Seroquel, the information leaflet that comes with the drug is your first guide. Always read this information before you start taking this drug and whenever you get a refill. The doctor’s instructions are another guide for taking Seroquel.

Seroquel is taken orally, usually twice or thrice a day. You can choose whether to take it with food or without food. If you’re taking this drug to treat bipolar disorder, you can take a daily dose at bedtime.

There is no fixed dosage for Seroquel. It’s all dependent on your response to treatment, your medical condition, and any other medications you might be taking.

Many physicians start their patients with a low dose of Seroquel to reduce possible side effects. As the patient adapts, they’ll slowly increase the dose.

Never increase your dose without your doctor’s consent or take it longer than prescribed. Doing this won’t improve your condition. Instead, you’ll be at risk of suffering side effects.

One thing to note is to take Seroquel regularly to receive the best benefits. You can also decide to take it at the same time every day to help you remember.

Side Effects

You might feel side effects like diarrhea, headaches, trouble sleeping, or nausea while taking Seroquel. Don’t be alarmed, as a gradual reduction in the dosage of this drug can resolve these side effects. If things don’t get better, you are free to inform your doctor.

Weight gain, upset stomach, blurred vision, constipation, drowsiness, and dry mouth are other common side effects of Seroquel. You should inform your doctor if these effects are long-lasting or if they’re getting worse.

Most people also feel lightheaded when they take Seroquel, and this can increase the risk of falling. So, patients with this side effect are advised to always get up slowly from any sitting or lying position.

The side effects of Seroquel can also get worse in rare cases, leading to symptoms like:

  • Constant abdominal pain
  • Depression
  • Trouble breathing during sleep
  • Non-stop vomiting
  • Thoughts of suicide
  • Restlessness
  • Shakiness
  • Yellowing eyes
  • Difficulty swallowing
  • Increased anxiety
  • Loss of appetite
  • Trouble urinating

Although allergic reactions to Seroquel are rare, they do happen, and the symptoms include:

  • Fever
  • Rash
  • Swollen lymph nodes
  • Itching of the tongue
  • Swelling of the face
  • Trouble breathing
  • Severe dizziness

Precaution

On rare occasions, Seroquel can raise blood sugar, which worsens diabetes in sufferers. As such, you should inform your doctor if you have high blood sugar before taking this medication. Diabetic patients who are taking this drug should remember to check their blood sugar levels regularly.

Seroquel can also cause a rise in cholesterol levels or significant weight gain in certain patients. When this is combined with diabetes, those patients are at risk of developing heart disease.

While taking Seroquel, keep your pharmacist informed about other medications you might be taking. This includes prescription drugs, herbal products, and non-prescription drugs.

Seroquel may also increase the production of prolactin in the body. In females, this can result in difficulty becoming pregnant, missed periods, or unwanted breast milk. For males, this condition can cause enlarged breasts, a decrease in sexual desires, or the inability to produce sperm.

Sometimes, Seroquel can cause prolonged or painful erections in males for more than four hours. People with such experiences should contact their doctor immediately.

Certain allergies get triggered due to the ingredients in Seroquel. So, you should ensure your doctor is aware of any allergies you may have before taking this drug.

Ensure your doctor is aware of your medical history, especially if you’ve suffered from diseases like:

  • Low white blood cell count
  • Eye cataracts
  • Trouble swallowing
  • Seizure disorder
  • Stomach blockage
  • Liver disease
  • Thyroid problems
  • Diabetes
  • Heart disease
  • High blood pressure
  • Sleep apnea
  • Difficulty urinating

Summing Up

To get the best benefits from Seroquel, ensure you follow your doctor’s instructions. Never stop taking this drug without your physician’s awareness or for longer than necessary.

Although Seroquel is popularly used as a sleep medication, this is not advisable. The benefits do not outweigh the possible risks in this case.