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Prednisolone is a drug that’s used to calm an overactive immune system and reduce inflammation. The most common form of Prednisolone is the pill, which is taken orally. However, there are other forms of this drug that can be used as eye drops, as skin cream, or injected into the veins.

Description and Uses

Prednisolone is a steroid hormone that’s used to treat numerous inflammatory conditions, autoimmune disorders, allergies, and cancers. This medication was approved for medical use in 1955.

The effects of Prednisolone are like cortisol. It does it jobs by preventing the body from releasing substances that cause inflammation.

Prednisolone is a corticosteroid with low mineralocorticoid and dominant glucocorticoid activity. So it doesn’t affect the body’s balance of water and electrolytes. This makes this medication a good choice for treating many autoimmune and inflammatory conditions, such as:

  • Asthma
  • Urticaria
  • Temporal arteritis
  • Pyoderma gangrenosum
  • Uveitis
  • Crohn’s disease
  • Cluster headaches
  • Rheumatoid arthritis
  • Kawasaki disease
  • Angioedema
  • Bell’s palsy
  • Sarcoidosis

Many doctors also prescribe Prednisolone as an immunosuppressive drug for organ transplants. People with allergies, whether seasonal or drug-induced, are also advised to use this medication. In small doses, Prednisolone can also be used by patients with Addison’s disease.

Consumption and Dosage

Take Prednisolone exactly as your doctor prescribes. This could be daily, with doses changing occasionally, or every other day.

Don’t take the Prednisolone disintegrating tablets out of their blister pack until you’re ready to take them. Ensure your hands are dry when opening the pack, and peel back the foil all the way. This way, you don’t have to force the tablet through the foil.

When you place the Prednisolone disintegrating tablet in your mouth, give it some time to dissolve. Do not chew, and make sure to swallow frequently as the tablet dissolves. If you’re having trouble swallowing, you can also drink water.

Taking Prednisolone can cause many medical tests to report false results. So, make sure your doctor knows you are taking this medication before conducting any tests.

What Happens If I Miss a Dose?

Call your doctor whenever you miss a dose of Prednisolone. There’s a chance that subsequent doses of your medication might need to change.

What Happens When I Overdose?

Unlike other medications, an overdose of Prednisolone isn’t fatal, nor is it expected to produce life-threatning symptoms. However, a long-term overdose can lead to other complications, like:

  • Thinning skin
  • Loss of interest in sex
  • Increase acne on the body
  • Changes in the shape of body fat
  • Easy bruising
  • Menstrual problems
  • Increased facial hair
  • Impotence

Side Effects

Taking Prednisolone can lead to some common side effects, like:

  • Swelling in the hands and ankles
  • Muscle pain
  • Changes in menstrual periods
  • Dizziness
  • Headache
  • Stomach discomfort or bloating

In rare cases, Prednisolone can lead to serious side effects, which would require you to contact your physician.

  • Shortness of breath
  • Severe depression
  • Rapid weight gain
  • Changes in personality
  • Increased thirst
  • Bruising
  • Coughing up blood
  • Seizure
  • Increased urination
  • Unusual pain in the arm or leg
  • Thinning skin
  • Nausea
  • Leg cramps
  • Vomiting
  • Irregular heartbeats
  • Bloody stools
  • Severe pain the upper back

There is also a situation where emergency medical attention is required, and this is when you notice the symptoms below:

  • Hives
  • Swelling of the tongue or face
  • Difficulty breathing

Prednisolone can lead to an abnormal growth rate in children. If your children are growing abnormally, you should contact your doctor immediately.

Precaution

While taking this steroid medication, avoid staying near people with infections. If you happen to be exposed to someone with chickenpox or measles, you’ll need to meet your doctor for preventive measures. Meeting people with these infections while taking steroid medications can be fatal.

Avoid live vaccines while taking Prednisolone. These vaccines may not work as they should during this period and won’t be able to protect you from the disease. Some of the live vaccines that you should avoid while taking this medication include:

  • Yellow fever
  • Measles
  • Rubella
  • Zoster
  • Nasal flu
  • Mumps
  • Polio

Avoid Prednisolone if yu’re suffering a fungal infection. Steroids can worsen any infections that you may already have. So, ensure that your doctor is aware of this before they prescribe this drug.

You should also make your physician aware of any illnesses or infections you may have had in the past few weeks. This is important if you’ve suffered from:

  • Thyroid disorder
  • Active tuberculosis
  • Psychosis
  • Stomach ulcer
  • Depression
  • Herpes infection of the eyes
  • Liver disease
  • Muscle disorder
  • High blood pressure

You should also inform your doctor if you have diabetes before taking this medication. That’s because steroid medications can increase the sugar level in the blood. So, there’s a good chance that you might need to adjust your doses of diabetes medication.

How to Store Prednisolone

Store Prednisolone at room temperature and away from heat. This means that you shouldn’t store this medication in direct sunlight or in the bathroom. You should also store Prednisolone in a location where children or pets cannot reach it.

Bottom Line

Follow your doctor’s instructions strictly when taking Prednisolone. Note that this drug shouldn’t be taken for longer than necessary, as this can lead to complications.

Do not stop taking Prednisolone abruptly. Always wait for the doctor’s go-ahead before tapering your dosage slowly.